Reproduction of companion animals
The most recent research projects of the team of reproduction of companion animals involve:
Canine reproductive microbiome
Recently, the importance of the resident bacterial populations in different body niches has been recognized, starting with the gut microbiome. Similarly, the reproductive organs host characteristics bacterial populations contributing to health and fertility. For this reason, concerns about the use of antibiotics are arising. The misuse of antibiotics can lead to unbalances in the microbiome and to emerging antimicrobial resistances by different bacteria. We are currently conducting research on the vaginal and seminal microbiomes in health and disease, to elucidate the role of resident bacteria in fertility and reproductive performances.
– Penelope Banchi & Lotte Spanoghe
Welcome fertility!
In this new innovative research project, planned for 2024, we build further on the reproductive microbiome research, but with a potentially great application in canine reproduction. Here we will test the impact of the supplementation of a specially developed reproductive probiotic on sperm quality and sperm freezing. This probiotic contains live microorganisms that are intended to have health benefits when they are consumed.
– Penelope Banchi, Lotte Spanoghe, Guillaume Domain, Joke Lannoo, Florin Posastiuc
Canine sperm cryopreservation
Sperm cryopreservation is a valuable tool in assisted reproduction to improve genetic diversity in dogs. However, the cryopreservation of dog spermatozoa is hampered by individual variability in sperm cryotolerance, confining its application to a selection of dogs. In this line of research, our group aims to optimize sperm cryopreservation for these specific dogs by developing multiple cryopreservation protocols and identifying predictors capable of determining the most appropriate protocol for these individuals.
– Guillaume Domain
Impact of neutering bitches and male dogs on long-term health
Neutering your dogs has many advantages, with the obvious one limiting the occurrence of unwanted litters. Besides that, an important reason is the prevention of heat symptoms (unwanted sexual behaviour, running away from home and vaginal blood loss) which bother some of the owners. Finally, neutering decreases the prevalence of pyometra and mammary tumours. Unfortunately, neutering also has some disadvantages, like a higher risk for obesity and coat changes and a possible increase of anxiety and aggressive behaviour. Furthermore, there is an increased risk for certain orthopaedic problems and the development of urinary incontinence. Recently, some studies pointed out that certain breeds have an increased risk developing neoplasia after neutering.
We are currently investigating if we can observe these recently documented side effects more common in neutered bitches and dogs compared to intact females and males, presented at the faculty of veterinary medicine.
– Guillaume Domain, Joke Lannoo, Penelope Banchi
Sperm preservation in non-domestic species
Nowadays, many animal species are considered as endangered due to low reproductive success. One of the reasons for this is the modification of their natural habitat due to human intervention. Assisted reproductive technologies are a powerful tool for reproductive success. Specifically, sperm collection, cryopreservation, and storage are essential to preserve genetic material for future use. Therefore, we are currently focusing on improving sperm collection and cryopreservation protocols in model non-domestic species, with a recent specific focus on reptiles.
– Penelope Banchi