Bruce Poppe
- Clinical geneticist
- Head of PrOZA - UZ Gent
- Full Professor
- Teamleader Societal Outreach
- Secretary - Belgian Association of Specialist Physicians in Clinical Genetics
- Alumni Coordinator - Faculty of Medicine and Health Sciences
Contact
Campus UZ, C. Heymanslaan 10, K5 (entrance 81), 9000 Ghent
E-mail I X (Twitter) | UGent Research Explorer | ORCID
Personalia
Biography
- 2018: Certificate in Clinical Genetics
- 2016 - 2023: Head of Center for Medical Genetics - UZ Gent
- 2015 - present: Coordinator of the Program for Undiagnosed Rare Diseases (PrOZA) - UZ Gent
- 2014 - present: Head of the Hospital function for Rare Diseases - UZ Gent
- 2008 - present: Professor - Ghent University
- 2006 - 2016: Senior Clinical Investigator FWO
- 2005: Specialist Physician - UZ Gent
- 2005: Certificate in Internal Medicine
- 2005: PhD - Ghent University
- 1997: Master Medicine - Ghent University
Member of
- Cancer Research Institute Ghent
- Center of Medical Genetics Ghent
- ERDERA
- Flemish network for rare diseases
- Fund for rare diseases
- GUARD
- Research consortium for rare diseases
- Solve-RD
- UDNI
Research tracks
Expertise
Clinical genetics and functional multi-omics of undiagnosed rare diseases.
Publications
Key publications
- Loss of phospholipase PLAAT3 causes a mixed lipodystrophic and neurological syndrome due to impaired PPARγ signaling. (2023) Nature Genet.
- Shortcutting the diagnostic odyssey: the multidisciplinary Program for Undiagnosed Rare Diseases in adults (UD-PrOZA). (2022) Orphanet J. Rare Dis.
- Breast-cancer risk in families with mutations in PALB2. (2014) N. Engl. J. Med.
- PHF6 mutations in T-cell acute lymphoblastic leukemia. (2010) Nature Genet.
- Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies. (2004) Blood