Prof. Christophe Ampe
- Senior Full Professor
- Head of the Actin and Cell Migration lab
- Teamleader Education
Contact
Campus Ardoyen, Technologiepark-Zwijnaarde 75, 9052 Ghent
E-mail | LinkedIn | UGent Research Explorer | Orcid
Personalia
Biography
- 2000 - present: Professor - Ghent University
- 1992 - 2000: Postdoc - Ghent University
- 1988 - 1992: Postdoc - Yale University
- 1987: PhD - Ghent University
- 1982: Master Biochemistry - Ghent university
Member of
Research tracks
Expertise
- Investigation of actin-based cell migration and cancer cell invasion via protein-focused approaches
- Expertise in biochemistry, molecular biology and imaging-based in vitro (preclinical) analysis
- Development of software tools for image processing and for standardized quantitative analysis of cell migration
- Fundamental research on actin regulation in disease (e.g. HIV, testin-family)
- Improvement of drug treatments (e.g. hepatocellular carcinoma, use of bacterial peptides)
Publications
Key publications
- Time for rethinking the different B-actin transgenic mouse models? (2020) Cytoskeleton.
- Prevalence of cytoplasmic actin mutations in diffuse large B-cell lymphoma and multiple myeloma : a functional assessment based on actin three-dimensional structures. (2020) International Journal of Molecular Sciences.
- Community standards for open cell migration data. (2020) Gigascience.
- A new evolutionary model for the vertebrate actin family including two novel groups. (2019) Molecular Phylogenetics and Evolution.
- Combination of EGFR inhibitor lapatinib and MET inhibitor foretinib inhibits migration of triple negative breast cancer cell lines. (2019) Cancers.