Christophe Ampe
- Senior Full Professor
- Head of the Cell Migration lab
Contact
Campus Ardoyen, Technologiepark-Zwijnaarde 75, 9052 Ghent
E-mail | LinkedIn | UGent Research Explorer | Orcid
Personalia
Biography
- 2000 - present: Professor - Ghent University
- 1996 - 2011: VIB Group Leader
- 1995 - 2000: FWO Research Associate
- 1992 - 1995: FWO Postdoc - Ghent University
- 1988 - 1992: Postdoc - Yale University (lab of Tom Steitz, Nobel laureate Chemistry, 2009)
- 1987: PhD - Ghent University
- 1982: Master Biochemistry - Ghent University
Fun fact
I hiked to the summit of mount M’Goun (4071 m) when I was 58. My training program was running up the stairs of K3 (not the mountain, just take entrance 42 at the UZ campus and skip the elevators).
Member of
- Cancer Research Institute Ghent
- European Cytoskeletan Forum (chairman 2000-2016)
- Ghent University MemClip consortium
Research tracks
Expertise
- Understanding actin and actin regulation in cancer biology
- Actin-based cell migration and cancer cell invasion via protein-focused research
- Expertise in biochemistry, molecular cell biology and imaging-based in vitro (preclinical) analysis for validating systems biology approaches
- Understanding the action of bacterial peptides as potential anti-cancer drugs on preclinical models
Publications
Key publications
- Multisite assessment of reproducibility in high‐content cell migration imaging data. (2023) Mol. Syst. Biol.
- Prevalence of cytoplasmic actin mutations in diffuse large B-cell lymphoma and multiple myeloma : a functional assessment based on actin three-dimensional structures. (2020) Int. J. Mol. Sci.
- Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity. (2012) Mol. Cell. Proteomics
- Pathway leading to correctly folded beta-tubulin. (1996) CELL
- Fragments of the HIV-1 Tat protein specifically bind TAR RNA. (1990) Science