Jo Vandesompele

• Full Professor
• Co-Head of the OncoRNALab

Contact

Campus UZ, C. Heymanslaan 10, Blok B (entrance 36), 9000 Ghent

Postal address: Campus UZ, C. Heymanslaan 10, MRB1 (entrance 34), 9000 Ghent

E-mail   |   LinkedIn    |   X (Twitter)    |    UGent Research Explorer   |   ORCID

Personalia

Biography

• 2007 - present: Professor - Ghent University
• 2002: PhD - Ghent University
• 1997: Master Bioscience Engineering - Ghent University

Fun fact

Things I like to do in my spare time: running and cycling, walking with my family, enjoying good food and drinks, camping with family, and making fire.

Member of

• Cancer Research Institute Ghent
• DIGPCR Digital PCR Center
• pxlence
• BIOMARKED

Research tracks

Expertise

Through a combination of nucleic acid quantification method development (digital PCR, RNA sequencing, spatial transcriptomics) and applied bioinformatics, I seek to better understand the value of RNA in health and disease, with a focus on various types of cancer. I make use of human liquid biopsies and tissues from patients and animal model systems.

Publications

Key publications

• Longitudinal evaluation of serum microRNAs as biomarkers for neuroblastoma burden and therapeutic p53 reactivation. (2023) NAR Cancer.
• Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA. (2022) NAR Cancer.
• Charting Extracellular Transcriptomes in The Human Biofluid RNA Atlas. (2020) Cell Reports.
• Melanoma addiction to the long noncoding RNA SAMMSON. (2016) Nature.
• The miR-17-92 microRNA cluster regulates multiple components of the TGF-beta pathway in neuroblastoma. (2010) Molecular Cell. 

All publications

• Biblio UGent