Prof. Kaat Durinck
- Assistant Professor
- Co-head of the Pediatric Precision Oncology lab
Contact
Campus UZ, C. Heymanslaan 10, MRB1 (entrance 34), 9000 Ghent
E-mail I X (Twitter) | UGent Research Explorer | ORCID
Personalia
Biography
- 2021 - present: Professor - Ghent University
- 2016 - 2021: Postdoc - Ghent University
- 2016: PhD - Ghent University
- 2010: Master Biochemistry and Biotechnology - Ghent University
Fun fact
In her free time, Kaat loves playing the piano.
Member of
Research tracks
Expertise
- Technology driven research on pediatric cancer entities
- Integration of genomics and proteomics
- Assemble the power of multiple model systems guided by the expertise of (inter)national teams
- Translation of research findings to related cancer entities
- Combine targeted drugging options with immunomodulators and reorient towards novel therapeutic strategies such as targeted protein degradation with the design of a new generation of cancer drugs (e.g. PROTACs)
Publications
Key publications
- RRM2 is a target for synthetic lethal interactions with replication stress checkpoint addiction in high-risk neuroblastoma. (2020) BioRxiv.
- A novel TLX1 driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models. (2020) Leukemia.
- Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development. (2020) Embo Reports.
- A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-ALL through polyA and total RNA-seq. (2018) Haematologica.
- Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia. (2015) Leukemia.