Leen Van Troys
- Senior Full Professor
- Co-Head of the Cell Migration lab
Contact
Campus Ardoyen, Technologiepark-Zwijnaarde 75, 9052 Ghent
E-mail | LinkedIn | UGent Research Explorer | Orcid
Personalia
Biography
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2005 - present: Professor (currently 45%)- Ghent University
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2005 – 2009: Senior Postdoc VIB
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1998 - 2005: FWO Postdoc - Ghent University
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1998: PhD in Biotechnology- Ghent Universityµ
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1991: Educational Degree Chemistry- Ghent University
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1990: Master Chemistry, option biotechnology - Ghent University
Member of
Research tracks
Expertise
- Cancer cell migration and invasion in 2D and 3D cell models (spheroids).
- Role of deubiquitinases in advanced hepatocellular carcinoma
- Expertise in biochemistry of the actin cytoskeleton, in imaging-based cell based assays, in development of image processing software tools
- Understanding the action of bacterial peptides as potential anti-cancer drugs on preclinical models
Publications
Key publications
- Multisite assessment of reproducibility in high‐content cell migration imaging data. (2023) Mol. Syst. Biol.
- Analysis of invasion dynamics of matrix-embedded cells in a multisample format. (2018) Methods in Molecular Biology
- An end-to-end software solution for the analysis of high-throughput single-cell migration data. (2017) Sci. Rep.
- Unbalancing the phosphatidylinositol-4,5-bisphosphate-cofilin interaction impairs cell steering. (2009) Mol. Biol. Cell
- Listeria comet tails: the actin-based motility machinery at work. (2008) Trends Cell Biol.
- The actin binding site of thymosin beta4 mapped by mutational analysis. (1996) EMBO J.