Functional Paediatric Oncogenomics Lab
Research interests
The lab focuses on neuroblastoma, a childhood solid tumor arising from the sympathetic nervous system with poor prognosis for high-risk patients.
- Gain insights into the role of genes and signalling networks in initiation and development of childhood cancer
- by combining high throughput genomic (bulk and single cell) and proteomics technologies, cellular model systems (including organoids), transgenic animal models and human patient derived xenografts in both zebrafish and mice
- Gain insights into processes leading to treatment resistance as a guide towards precision medicine strategies
- focus on combination therapies using small molecules and PROTACs (proteolysis targeting chimera)
More information about the Functional Paediatric Oncogenomics Lab
More information about Prof. Frank Speleman
- Prof. Frank Speleman is co-supervisor of the Laboratory of Cytogenomics in the Center of Medical Genetics Ghent
- Prof. Frank Speleman is co-founder, previous member of the steering committee and current group leader of Cancer Research Institute Ghent
- Prof. Frank Speleman is member of the scientific board of Stichting Tegen Kanker
More information about Prof. Nadine Van Roy
- Prof. Nadine Van Roy is lab supervisor in the Center for Medical Genetics Ghent