Department of Biomolecular Medicine

Pediatric Precision Oncology Lab

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Kaat-Durinck.jpg     Nadine Van Roy

     Prof. Kaat Durinck            Prof. Nadine Van Roy

Research interests

The lab focuses on neuroblastoma, a childhood solid tumor arising from the sympathetic nervous system with poor prognosis for high-risk patients.

  • Gain insights into the role of genes and signalling networks in initiation and development of childhood cancer
    • by combining high throughput genomic (bulk and single cell) and proteomics technologies, cellular model systems (including organoids), transgenic animal models and human patient derived xenografts in both zebrafish and mice
  • Gain insights into processes leading to treatment resistance as a guide towards precision medicine strategies
    • focus on combination therapies using small molecules and PROTACs (proteolysis targeting chimera) 

More information about the Pediatric Precision Oncology Lab

More information about Prof. Frank Speleman

  • Prof. Frank Speleman is co-supervisor of the Laboratory of Cytogenomics in the Center of Medical Genetics Ghent
  • Prof. Frank Speleman is co-founder, previous member of the steering committee and current group leader of Cancer Research Institute Ghent
  • Prof. Frank Speleman is member of the scientific board of Stichting Tegen Kanker  

More information about Prof. Nadine Van Roy