4Brain
Background and research focus
Background
4Brain is a multidisciplinary research group focusing on translational neuroscientific research in epilepsy, stroke, Multiple Sclerosis, and cognitive problems, with a specific expertise on neuromodulation.
Research focus
Neuroscientists within 4BRAIN focus on translational neuroscience to unravel the pathophysiology of neuropsychiatric disorders and to develop novel therapies. Multimodal neuroscience techniques are used to excel in the neuroscience field and bridge preclinical and clinical research. The focus of our preclinical research is on advanced recording and neuromodulation techniques in various models for neuropsychiatric diseases to understand their pathogenesis and search for new treatments. The focus of our clinical research is on multimodal clinical techniques including neurophysiology, imaging and neuropsychology and on the modulation of aberrant brain function using both non-invasive and invasive neuromodulatory treatments.
Members
Professors and Guest Professors
Evelien Carrette (contact person)
Postdoctoral researchers
PhD candidates
Lien Naert (Department of Experimental psychology)
Ruben Schoeters (Department of Information technology)
Nicolas Vandenbussche (Ghent University Hospital)
Liesbeth Van Hijfte (Ghent University Hospital)
Kristof Verhoeven (Ghent University Hospital)
Technical staff
Ine Dauwe (Ghent University Hospital)
Jeroen Van Aken (extern)
National and international collaborations
National
UGent
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GHEP-lab: Chris Baeken, Marie-Anne Vanderhasselt
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Infinity: Chris Vanhove
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Department for Microsystems Technology (CMST): Jan Van Fleteren, Frederik Leys
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Medicinal Chemistry: Serge Van Calenberg
KU Leuven
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Laboratory for Neuro- and Psychophysiology: Marc Van Hulle
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Research Group for Neurobiology and Gene Therapy: Veerle Baekelandt
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NERF: Fabian Kloosterman
VUB
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Center for Neurosciences: Ilse Smolders, Dimitri De Bundel, Ann Massie, Ann Van Eeckhaut (formal longstanding collaboration via AMIE)
ULB-Erasme
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Laboratoire de Cartography fonctionelle du Cerveau & MEG unit
UCL-Louvain
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Institute for Neuroscience: Philippe Gailly, Jean-Noel Octave
International
- Technical University Eindhoven: Bert Aldenkamp, Jan Bergmans, Rob Mestrom, Sveta Zinger, Maarten Paulides, Massimo Mischi, …
- Donders Institute: Lennart Verhagen
- University of IRVINE: Bruce McNaughton
- University of Barcelona: Francisco Ciruela
Defended PhDs (last 5 years)
Preclinical evaluation of chemogenetics as a new treatment for drug-resistant epilepsy
Jana Desloovere (2022)
Silke Proesmans (2022)
Optogenetic modulation of hippocampal excitability and seizures
Anirudh Acharya (2022)
Charlotte Germonpré (2021)
The potential of transcutaneous auricular vagus nerve stimulation to improve epilepsy and cognition
Ann Mertens (2021)
Charlotte Bouckaert (2021)
Emma Christiaen (2021)
Latoya Stevens (2021)
A friend in need is a friend indeed : the benefits of the Human-Animal Bond during challenging times
Ana Martos Martinez-Caja (2021)
Stephanie Hödl (2021)
Anne Sieben (2021)
Elien De Cock (2021)
Chemogenetic neuromodulation in a rat model of epilepsy
Marie-Gabrielle Goossens (2021)
Temperature as a confounder on vagus nerve stimulation induced brain excitability modulation in rats
Wouter Van Lysebettens (2020)
Deep brain stimulation for drug-resistant epilepsy: efficacy and mechanism of action
Mathieu Sprengers (2020)
Deborah Klooster (2019)
Understanding consumers' food experience through measurement of explicit and implicit responses
Sofie Lagast (2017)
Albert Colon (2017)
Investigation of a role of uric acid in experimental seizure models
Lisa Thyrion (2016)
Investigation of the neurophysiological mechanisms of vagus nerve stimulation
Lars Emil Larsen (2016)
Event-related potentials in patients with refractory epilepsy
Leen De Taeye (2015)
Vagus nerve stimulation for epilepsy and depression: mechanism of action and stimulation parameters
Annelies Grimonprez (2015)
Ine Buffel (2015)
Hippocampal deep brain stimulation for drug resistant epilepsy in a rodent model
Bregt Van Nieuwenhuyse (2015)